Richard Owczarzy

Nucleic acid biophysics

 

Richard Owczarzy - photo
My biophysics research group at Integrated DNA Technologies  is focused on properties and functions of nucleic acids. We split duplexes to measure their stabilities and explore how ions, small organic molecules, and proteins interact with nucleic acids. We connect artificial molecules to nucleic acids aspiring to modify DNA character and provide new features. To help design better oligonucleotides, my group created software tools that predict properties of nucleic acids, including thermodynamics, melting temperature, folding, hybridization, and secondary structure.