My biophysics research group at
Integrated DNA Technologies is
focused on properties and functions of nucleic acids. We split duplexes to
measure their stabilities and explore how ions, small organic molecules, and
proteins interact with nucleic acids. We connect artificial molecules to nucleic
acids aspiring to modify DNA character and provide new features. To help design
better oligonucleotides, my group created software tools that predict
properties of nucleic acids, including thermodynamics, melting temperature,
folding, hybridization, and secondary structure.