Richard Owczarzy

Nucleic acid biophysics

My publications

Stability and mismatch discrimination of locked nucleic acid-DNA duplexes (2011) Biochemistry 50, 9352-9367. Abstract Reprint
Nucleotide bias observed with a short SELEX RNA aptamer library (2011) Nucleic Acid Therapeutics 21, 253-263. Abstract Reprint
Measuring thermodynamic details of DNA hybridization using fluorescence (2011) Biopolymers 95, 472-486. Abstract Reprint
IDT SciTools: a suite for analysis and design of nucleic acid oligomers (2008) Nucleic Acids Research, 36 (Supplement 2), W163-W169. Abstract Reprint
Predicting stability of DNA duplexes in solutions containing magnesium and monovalent cations (2008) Biochemistry 47, 5336-5353. Abstract Reprint Additional data
Predicting ultraviolet spectrum of single stranded and double stranded deoxyribonucleic acids (2008) Biophysical Chemistry 133, 66-70. Abstract Reprint Supplementary Data
Design of LNA probes that improve mismatch discrimination (2006) Nucleic Acids Research 34, e60. Abstract Reprint Supplementary data
Studies of DNA dumbbells VIII. Melting analysis of DNA dumbbells with dinucleotide repeat stem sequences (2006) Biopolymers 82, 199-221. Abstract Reprint
Melting temperatures of nucleic acids: Discrepancies in analysis (2005) Biophysical Chemistry 117, 207-215. Abstract Reprint
Effects of fluorescent dyes, quenchers, and dangling ends on DNA duplex stability (2005) Biochemical and Biophysical Research Communications 327, 473-484. Abstract Reprint Supplementary data
Effects of sodium ions on DNA duplex oligomers: Improved predictions of melting temperatures (2004) Biochemistry 43, 3537-3554. Abstract Reprint Supplementary data
Thermodynamic treatment of oligonucleotide duplex-simplex equilibria (2003) Proc. Natl. Acad. Sci. USA 100, 14840-14845. Abstract Reprint
Comments on "Calculation of the Energy of Transition Associated with Inversion in Double-Stranded DNA" [P.Aggarwal, D. Dollimore, Thermochim. Acta 284 (1996) 109]: a test (2001) Thermochimica Acta 373, 153-160. Abstract Reprint
Calculating sequence-dependent melting stability of duplex DNA oligomers and multiplex sequence analysis by graphs (2001) Methods Enzymol. 340 (Drug-nucleic acid interactions), 165-192. Abstract Reprint
Studies of DNA dumbbells VII: Evaluation of the next-nearest-neighbor sequence-dependent interactions in duplex DNA (1999) Biopolymers 52, 29-56. Abstract Reprint
Predicting sequence-dependent melting stability of short duplex DNA oligomers (1997) Biopolymers 44, 217-239. Abstract Reprint
Studies of DNA dumbbells. VI. Analysis of optical melting curves of dumbbells with a sixteen-base pair duplex stem and end-loops of variable size and sequence (1996) Biopolymers 39, 779-793. Abstract Reprint
Ph.D. Thesis, Richard Owczarzy (1999) Predictions of short DNA duplex thermodynamics and evaluation of next nearest neighbor interactions. University of Illinois at Chicago. Abstract Full text