Richard Owczarzy

My publications

• Rapid detection of urinary tract infections via bacterial nuclease activity (2017) Molecular Therapy 25, 1353–1362. Abstract Reprint
• Cy3 and Cy5 dyes attached to oligonucleotide terminus stabilize DNA duplexes: Predictive thermodynamic model (2015) Biophysical Chemistry 198, 36-44. Abstract Reprint
• Improved performance of anti-miRNA oligonucleotides using a novel non-nucleotide modifier (2013) Molecular Therapy Nucleic Acids 2, e117. Abstract Reprint
• Oligonucleotide primers and probes: Use of chemical modifications to increase or decrease the specificity of qPCR (2013) Real-Time PCR: Advanced Technologies and Applications (Saunders, N.A. and Lee, M.A., Editors) 2003, 171-198. Abstract Reprint
• Stability and mismatch discrimination of locked nucleic acid-DNA duplexes (2011) Biochemistry 50, 9352-9367. Abstract Reprint
• Nucleotide bias observed with a short SELEX RNA aptamer library (2011) Nucleic Acid Therapeutics 21, 253-263. Abstract Reprint
• Measuring thermodynamic details of DNA hybridization using fluorescence (2011) Biopolymers 95, 472-486. Abstract Reprint
• IDT SciTools: a suite for analysis and design of nucleic acid oligomers (2008) Nucleic Acids Research, 36 (Supplement 2), W163-W169. Abstract Reprint
• Predicting stability of DNA duplexes in solutions containing magnesium and monovalent cations (2008) Biochemistry 47, 5336-5353. Abstract Reprint Additional data
• Predicting ultraviolet spectrum of single stranded and double stranded deoxyribonucleic acids (2008) Biophysical Chemistry 133, 66-70. Abstract Reprint Supplementary Data
• Design of LNA probes that improve mismatch discrimination (2006) Nucleic Acids Research 34, e60. Abstract Reprint Supplementary data
• Studies of DNA dumbbells VIII. Melting analysis of DNA dumbbells with dinucleotide repeat stem sequences (2006) Biopolymers 82, 199-221. Abstract Reprint
• Melting temperatures of nucleic acids: Discrepancies in analysis (2005) Biophysical Chemistry 117, 207-215. Abstract Reprint
• Effects of fluorescent dyes, quenchers, and dangling ends on DNA duplex stability (2005) Biochemical and Biophysical Research Communications 327, 473-484. Abstract Reprint Supplementary data
• Effects of sodium ions on DNA duplex oligomers: Improved predictions of melting temperatures (2004) Biochemistry 43, 3537-3554. Abstract Reprint Supplementary data
• Thermodynamic treatment of oligonucleotide duplex-simplex equilibria (2003) Proc. Natl. Acad. Sci. USA 100, 14840-14845. Abstract Reprint
• Comments on "Calculation of the Energy of Transition Associated with Inversion in Double-Stranded DNA" [P.Aggarwal, D. Dollimore, Thermochim. Acta 284 (1996) 109]: a test (2001) Thermochimica Acta 373, 153-160. Abstract Reprint
• Calculating sequence-dependent melting stability of duplex DNA oligomers and multiplex sequence analysis by graphs (2001) Methods Enzymol. 340 (Drug-nucleic acid interactions), 165-192. Abstract Reprint
• Studies of DNA dumbbells VII: Evaluation of the next-nearest-neighbor sequence-dependent interactions in duplex DNA (1999) Biopolymers 52, 29-56. Abstract Reprint
• Predicting sequence-dependent melting stability of short duplex DNA oligomers (1997) Biopolymers 44, 217-239. Abstract Reprint
• Studies of DNA dumbbells. VI. Analysis of optical melting curves of dumbbells with a sixteen-base pair duplex stem and end-loops of variable size and sequence (1996) Biopolymers 39, 779-793. Abstract Reprint
• Ph.D. Thesis, Richard Owczarzy (1999) Predictions of short DNA duplex thermodynamics and evaluation of next nearest neighbor interactions. University of Illinois at Chicago. Abstract Full text